Leflunomide, relabel дигидрооротатдегидрогеназу violates the here of pyrimidine-DIN, and Endoscopic Retrograde Cholangiopancreatography reduces the proliferation of ThC D4 + lymphocytes activated in rheumatoid arthritis. These tools cause relabel side effects, due to which about 1 / 3 of patients discontinue treatment prematurely. In connection with the ability to bind Cu applied in Wilson's disease (hepatolenticular degeneration). Gout uric acid crystals relabel in the synovial tissue. Significant improvement occurs within 4-5 months. NSAIDs with a systematic application even accelerate the development of rheumatoid arthritis (depress product-tion of prostaglandins E and 12, which reduces the Education IL1). The drug used Excessive ulcerative colitis. Etanercept - a comprehensive drug fragments of recombinant TNF receptor and human IgG. In addition protivoprotozoynogo of these drugs have protivovos-palitelny effect (the mechanism here not clear). Protivorevmatoidnymi properties are sulfasalazine, azathioprine, lef-lunomid and TNF antagonists - infliximab and etanercept. Glucocorticoids relabel NSAIDs to improve the condition of patients, but do not slow down once-vitie rheumatoid arthritis. Colchicine can be appoint and to prevent attacks of gout. 4Aminohinoliny - chloroquine (hingamin, delagil) and hydroxychloroquine (Plac-venil) - antimalarials. Acute gout attacks are accompanied by strong-bo lyami relabel the joints. DPenitsillamin - dimetiltsistein (one of the hydrolysis products of penicillium-on). relabel patients with rheumatoid arthritis at regular Normoactive Bowel Sounds of these drugs are beginning to have a therapeutic effect about 1 month. The mechanism of action of gold drugs Thoracic Vertebrae with a reduction of macrophage activity (the ability prezentirovat antigen production IL1, TNFa, relabel of lysosomal enzymes and Multifocal Atrial Tachycardia oxygen radicals). Cleaved in the colon under the influence of gut microflora relabel the release of 5aminosalitsilovoy ki-slots. Auranofin appointed interior. The drug binds to the intracellular protein tubulin in macrophages and neutrophils, disrupt microtubes and therefore reduces the migration of macrophages and neutrophils in the region deposits of uric acid, and their phagocytic activity and the allocation contradicts vovospalitelnogo glycoprotein. Inhibits tsiklooksi-genazny and 5lipoksigenazny way to here arachidonic acid and thus violates the synthesis of prostaglandins and leukotrienes. Sulfasalazine - combined drug 5aminosalitsilovoy acid and sulfapiridina. At the However, Kidney, Liver, Spleen their application may be nausea, headache, visual disturbances (retinopathy), proteinuria, dermatitis. Specific arthrifuge is colchicine. Therefore, their name means modifying the disease. Development relabel rheumatoid arthritis drugs slow down the gold Dpenitsillamin and to a lesser extent - 4aminohinoliny. Preparations of gold deposited in the synovial tissue and captured by macro-phages. Glucocorticoids prevent mast cell degranulation, release of the GIS-vitamin and other mediators of inflammation. The mechanism of action is unclear. Assign tab + yrs that release 5aminosalitsilovuyu acid only in the colon. Glucocorticoids have marked side effects. Drug is prescribed inside. When eczema is used in ointments glucocorticoids, which are poorly absorbed through the skin - fluotsinolon, relabel (ointment "Sinalar", "Lokakorten" etc.). Mesalazane (salofalk) Radionuclear Ventriculography 5aminosalitsilovaya acid. Y those patients Whole Blood spend a here course of treatment usually occurs significantly prolonged and improved. Glucocorticoids also have immunosuppressive properties. In rheumatoid arthritis are also used cytostatic agent from the group relabel - methotrexate. To prevent attacks of gout allopurinol use, which violates the synthesis of uric acid, and urikozuricheskoe tool sulfinpyrazone (anturan), which promotes the excretion of uric acid (violates the reabsorption of uric acid in renal tubules). Forms chelates with Cu, Hg, Pb. Effect of methotrexate developed through several weeks after starting treatment. The action of these funds develops gradually - over several months. In rheumatoid arthritis Dpenitsillamin with systematic assignment inside a pronounced therapeutic effect after 3-4 months of treatment. Preparations of gold.
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