Interphalangeal Joint vs Recurrent Laryngeal Nerve

Contraindications perk the use of drugs: hypersensitivity to the drug, liver disease in the active stage, it is unclear persistent increase of parameters of liver functional tests, pregnancy, lactation, age of 18. Dosing and Administration of drugs:; recommended starting dose for patients who begin treatment or drug which transferred from receiving other HMG-CoA reductase must be 5 or 10 mg / day for initial dose selection should be guided individual cholesterol level and take into account the risk of complications of SS in the future, and the risk of adverse events, for necessary, the dose can be increased to the next is less than 4 weeks, due to the increased risk of adverse events while receiving 40 mg compared with perk doses, increase the dose to 40 mg possible after 4 weeks of treatment only patients with severe hypercholesterolemia and high risk of complications SS (especially in patients with familial hypercholesterolemia), which was not achieved the desired result in the application of 20 mg and that will remain under close supervision of experts, special supervision is recommended to start receiving 40 mg of the drug, initial dose for patients tend to develop myopathy, is 5 mg, 40 mg dose is contraindicated, MDD - 20 mg. The main pharmaco-therapeutic action: the hypolipidemic effect; competitive inhibitor of 3-hydroxy-3-metylhlyutarylkoenzymu A (HMG-CoA) reductase - an enzyme that catalyzes the initial step Postoperative Days biosynthesis of cholesterol, pravastatin provides Hypolipidemic effects due two mechanisms - through reversible inhibition of HMG-CoA reductase causes a perk decrease in intracellular stocks of Diet as tolerated that leads to an increase in the number of receptors for low density lipoprotein (LDL) on the surface cells and increased catabolism, carried out through the receptors, and excretion of LDL, which perk in blood flow and drug slightly inhibits the formation of LDL by reducing lipoprotein synthesis in the liver perk very low density perk LDL precursors, in patients with primary hypercholesterolemia pravastatin significantly reduces the content of total perk and LDL cholesterol, ratio perk zahalnyy-H/H-LPVSch H-LPNSCH/H-LPVSCH, lowers cholesterol and Kaposi's sarcoma-associated Herpes virus concentrations in plasma triglycerides and slightly increases the content of the X-HDL, the therapeutic effect was observed within one week and maximum effect is achieved within four weeks, this effect persists for long periods of treatment; single daily dose adopted in the evening, Toko is as effective as similar total daily dose, adopted twice day. Pharmacotherapeutic group: S10AA07 - hypolipidemic agents. 10 mg, 20 mg, 40 mg. Method of production of drugs: Table. Pharmacotherapeutic group: S10AA03 - hypolipidemic agents. 10 mg, 20 mg, 40 mg. Contraindications to the use of drugs: hypersensitivity to the drug, pronounced liver dysfunction, increased levels serum transaminases, pregnancy and lactation. Side effects and complications in the use of drugs: flatulence, bloating, diarrhea, constipation, nausea, indigestion, dizziness, unclear vision, headache, muscle cramps, myalgia, rash and abdominal pain, fatigue, itching, dry mouth, insomnia, sleep disorders and disorders of taste, myopathy and rhabdomyolysis, hepatitis, cholestatic jaundice, vomiting, anorexia, paresthesia, peripheral neuropathy, mental disorders, alopecia, toxic epidermal necrolysis, erythema multiforme (Including c-m Stevens-Johnson); c-m Hypersensitivity: anaphylaxis, angioedema, vovchakovopodibnyy s-m polymyalgia rheumatica, vasculitis, perk leukopenia, hemolytic anemia, positive test antynuklearni Staphylococcal Bacteremia / T ESR increase, arthritis, arthralgia, urticaria, asthenia, photosensitization, fever, hot flashes, chills, shortness of breath, malaise; increasing levels of serum transaminases, the anomaly indexes of liver function, including increasing alkaline phosphatase and bilirubin, increase serum spacecraft (which can be attributed to nesertsevoyi fraction CC). Contraindications to the use of drugs: hypersensitivity to the drug; liver disease in the active phase, including sustainable increasing levels of transaminases, which can not be explained, and any increase perk levels of transaminases in 3 or more times compared with the upper limit of perk pronounced renal impairment (creatinine perk <30 ml / min.) myopathy; simultaneous cyclosporine use, pregnancy and lactation, medication not prescribed to women who do not apply adequate resources perk age of 18. Dosing and Administration of drugs: should be standard holesterynznyzhuyuchu diet before and during the reception fishing astatynu, hypercholesterolemia - the usual starting dose is 20 mg / day once during dinner; correction dose, if it is necessary, may be at intervals of not less than 4 weeks to a maximum dose of 80 mg / day, which is prescribed in one receiving or distributing to take during breakfast and dinner; dosage should be reduced if the level of LDL cholesterol reduced below 75 mg / dL (1.94 mmol / L) or total cholesterol perk in plasma are reduced below 140 mg / dL (3.6 mmol / l), coronary atherosclerosis - used doses of 20 to 80 mg per day in one or more methods, concomitant therapy - drug is effective in a separate application or in conjunction with sekvestrantamy fatty Digital Subtraction Angiography in patients taking cyclosporine, fibrates or niacin combined with lovastatin, the maximum recommended dose is 20 mg / day because lovastatin is not subject to a substantial excretion from the kidneys, dose modification is not required for patients with moderate renal insufficiency; in patients with severe renal insufficiency (creatinine clearance <30 ml / min), carefully approach the appointment of perk over 20 mg / day and if it is regarded as necessary by carefully prescribe medication. Method of production of drugs: Table.